SNPlinks: Web resources with forensic relevance

UniSTS LocusLink Dusseldorf STR Database Marshfield Center for Medical Genetics
ALFRED MitoMap Y-STR Database EMPOP Database
NIST STR Base      

NCBI UniSTS http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=unists

UniSTS collates linkage marker (mini- and microsatellite) and Sequence Tagged Site (STS) data. The database displays for each marker, the primer sequences, product size, and mapping information, as well as cross references to LocusLink, dbSNP and Entrez Map Viewer. As such it provides extensive data for STRs, queried using the D number (e.g. D21S11), accession number or, if necessary, a non-standard identifier (e.g. FGA).


NCBI LocusLink http://www.ncbi.nlm.nih.gov/LocusLink/

LocusLink is the main point of reference for all data relating to genes. It provides a single query interface to all the curated sequence plus descriptive information for known genes in humans (together with 9 other organisms). Data returned is cross referenced to other NCBI sections for: official nomenclature, aliases, sequence accessions, phenotypes, EC numbers, MIM (Mendelian Inheritance in Man) numbers, UniGene clusters, homology and map locations. This database is also an important reference source for checking the characteristics (and therefore possible significance of any linkage) of genes that may be in close proximity to candidate SNP markers.


The Dusseldorf STR Database http://www.uni-duesseldorf.de/WWW/MedFak/Serology/dna.html

An STR allele frequency database with lists of supporting publications.


The Marshfield Centre for Medical Genetics http://research.marshfieldclinic.org/genetics/Map_Markers/maps/IndexMapFrames.html

This site collates mapping information for a full range of polymorphisms. A useful alternative to LocusLink for locating STR positions.


Mitomap http://www.mitomap.org/

Database of polymorphisms and mutations of human mitochondrial DNA.


ALFRED (ALlele FREquency Database) http://alfred.med.yale.edu/alfred/index.asp

Comprises 856 polymorphisms, 377 populations and 17,569 frequency tables, including many standard forensic loci.


Y-STR & EMPOP Databases 

http://www.yhrd.org

http://www.empop.org

The principal forensic orientated Y chromosome STR and mtDNA sequence polymorphism databases.


The STRbase at the National Insitute of Standards and Technology

http://www.cstl.nist.gov/div831/strbase/

Contains extensive data on all types of STRs, a huge bibliography, beautiful presentations (ppt and pdf), as well as a compilation of forensic SNPs and SNP resources.


 

Chris Phillips 18.02.2004, last update Jan. 07